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Press release:
Immune T cells become exhausted in chronic fatigue syndrome patients

https://www.eurekalert.org/news-releases/1066876

Longer piece from same university with more quotes:
https://news.cornell.edu/stories/2024/12/immune-t-cells-become-exhausted-chronic-fatigue-syndrome-patients

#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME @mecfs
News Release 3-Dec-2024 Immune T cells become exhausted in chronic fatigue syndrome patients Peer-Reviewed Publication Cornell University ITHACA, N.Y. – Chronic fatigue syndrome creates conditions where pathogen-killing immune T cells become exhausted, according to a new Cornell University study. The study’s authors knew the immune system was dysregulated in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) but wondered which parts shift with the condition. A systematic exploration revealed that key CD8+ T cells displayed one of the most pronounced signatures of dysregulation, with signs of constant stimulation that lead to an exhausted state, a condition that is well-studied in cancer. “This is an important finding for ME/CFS because now we can examine the T cells more carefully, and hopefully by looking in the exhausted cells we can start to get hints as to what they are responding to,” said Andrew Grimson, professor of molecular biology and co-corresponding author of the study. Maureen Hanson, professor of molecular biology and genetics, is the other corresponding author.

Immune T cells become exhausted in chronic fatigue syndrome patients | Cornell Chronicle

The study found that key CD8+ T cells showed signs of constant stimulation that lead to an exhausted state, a condition that is well-studied in cancer.
Cornell Chronicle
#cfs #mecfs #pwme #MyalgicEncephalomyelitis #chronicfatiguesyndrome @MECFS group
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