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Here's the latest variant picture for the United States.

The XEC.* variant has been overtaken by the LP.8.1.* variant - growing steadily to around 34%.

There’s a rebound underway among the JN.1.* + FLiRT variants, led by the LB.1.3.1 lineage.

#COVID19 #USA #XEC #LP_8_1
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#COVID19 #usa #xec #lp_8_1
Mike Honey
Here are the leading US states reporting LP.8.1.*. Illinois has reported strong growth to 57%, and there is strong growth also in New York, New Jersey and California to around 40%.
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Mike Honey
For the US, the LP.8.1.* variant shows a steady growth advantage of 3.1% per day (22% per week) over the dominant XEC.* variant, with a crossover in mid-February.
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Mike Honey
Among the LP.8.1.* sub-lineages, the first child lineage LP.8.1.1 has been the most successful. Note the NY lineages are the descendants of LP.8.1.1.
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Mike Honey
LP.8.1.1 adds the K679R mutation, changing the furin cleavage site. The effect of this still seems unclear, hopefully more studies will clarify it.
https://threadreaderapp.com/thread/1894923514743865792.html
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Thread by @LongDesertTrain on Thread Reader App

@LongDesertTrain: Great new study on LP.8.1(.1). Provisional takeaways: • Slight increase in antibody evasion • No change in S1/S2 cleavage (despite additional R in LP.8.1.1 FCS (now RSRRRAR) • Possibly even stronge...…
threadreaderapp.com
Mike Honey
The rebound among the JN.1.* + FLiRT variants is led by the LB.1.3.1 lineage – most likely from recently-added mutations. There are a few new lineages proposed, so the picture should become clearer as more data becomes available.
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