Zum Inhalt der Seite gehen

Suche

Beiträge, die mit CORONAVIRUS getaggt sind


The Orexin System and Its Impact on the Autonomic Nervous and Cardiometabolic System in Post-Acute Sequelae of COVID-19

https://www.mdpi.com/2227-9059/13/3/545

From latest Science for ME weekly update

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 @auscovid19 #auscovid19
Biomedicines
The Orexin System and Its Impact on the Autonomic Nervous and Cardiometabolic System in Post-Acute Sequelae of COVID-19 — Ruhrländer et al.
Review. "We assume that several symptoms that occur after COVID-19 are due to an imbalance in the OX system. In particular, factors such as vascular tone, cardiac and endothelial function, lipid metabolism, and neuropeptide regulation are crucial to the pathophysiology of the OX system, as well as PASC."


Sympathetic article; quotes 3 German experts

"Years after the pandemic, has the threat of #LongCovid subsided?"

https://www.yahoo.com/news/years-pandemic-threat-long-covid-153323420.html

Includes this "Depending on the symptoms, doctors will often recommend exercise therapy ..." but then that can be true for people without PEM

@longcovid
#PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #SARSCoV2 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver

1/
dpa international
Years after the pandemic, has the threat of Long Covid subsided?
DPA
Mon, February 24, 2025 at 3:33 PM GMT5 min read


4
Many Long Covid sufferers first have to learn to accept that even small household tasks burn up a huge amount of energy. Annette Riedl/dpa
Many Long Covid sufferers first have to learn to accept that even small household tasks burn up a huge amount of energy. Annette Riedl/dpa
After the initial global shock of the pandemic, another followed. Some people, it emerged, were surviving an infection, but not making a full recovery.

About four years ago, it started to become clear that Sars-CoV-2, the coronavirus behind the pandemic, could impair mental and physical performance well beyond the initial infection.

The phenomenon of symptoms lasting longer than four weeks has long since been given a name - Long Covid. However, medicine is still a long way from curing the causes of such long-term effects.


Die vergessene Trauer der Angehörigen von Corona-Opfern

Vor gut fünf Jahren wurde der erste Corona-Fall in Deutschland festgestellt. Das unbekannte Virus sorgte für Angst und Unsicherheit. Angehörige von Verstorbenen leiden noch heute unter den Folgen der Einschränkungen. Von Jens Eberl.

➡️ https://www.tagesschau.de/inland/gesellschaft/jahrestag-corona-ausbruch-100.html?at_medium=mastodon&at_campaign=tagesschau.de

#Corona #Coronavirus #Pandemie


Ausbruch in Wuhan: USA und China streiten über Corona-Ursprung

Der neue CIA-Direktor hat die Einschätzung der Behörde zum Corona-Ursprung geändert: Der Geheimdienst hält jetzt einen Laborunfall für wahrscheinlicher. China weist die Theorie zurück - und beklagt Verleumdung.

➡️ https://www.tagesschau.de/ausland/amerika/cia-china-corona-100.html?at_medium=mastodon&at_campaign=tagesschau.de

#Corona #China #CIA #Coronavirus #USA #Wuhan #Trump


2020 hielt #Drosten einen natürl. Ursprung des #Coronavirus für wahrscheinlicher als einen Laborunfall in #Wuhan. Mittlerweise ist er da skeptischer, weil chines. Wissenschaftler*innen den natürl. Ursprung des Virus inzwischen hätten nachweisen können - es aber nicht taten.
Nun werden wieder alle auf ihn einprügeln, denen seine Infos schon 2020 nicht passten.
Aber mir ist ein Virologe, der offen zugibt, dass er nicht alles weiß, lieber als alle selbsternannten "Experten"!
https://taz.de/Christian-Drosten/!6061896/


Als vor fünf Jahren der weltweit erste Corona-Lockdown begann

Am 23. Januar 2020 verriegelten Sicherheitskräfte den Bahnhof in Chinas Millionenstadt Wuhan. Es war der erste Corona-Lockdown, auch wenn die Krankheit damals noch nicht so hieß. Benjamin Eyssel blickt zurück.

➡️ https://www.tagesschau.de/ausland/asien/wuhan-corona-jahrestag-102.html?at_medium=mastodon&at_campaign=tagesschau.de

#Coronavirus #China #Lockdown #Wuhan


Ongoing #Evolution of #MERS-CoV, #Saudi Arabia, 2023–2024


Source: Emerging Infectious Diseases Journal, https://wwwnc.cdc.gov/eid/article/31/1/24-1030_article

Abstract
Middle East respiratory syndrome coronavirus (MERS-CoV) circulates in dromedary camels in the Arabian Peninsula and occasionally causes spillover infections in humans. MERS-CoV diversity is poorly understood because of the lack of sampling during the COVID-19 pandemic. We collected 558 swab samples from dromedary camels in Saudi Arabia during November 2023–January 2024. We found 39% were positive for MERS-CoV RNA by reverse transcription PCR. We sequenced 42 MERS-CoVs and 7 human 229E-related coronaviruses from camel swab samples by using high-throughput sequencing. Sequences from both viruses formed monophyletic clades apical to recently available genomes. MERS-CoV sequences were most similar to B5 lineage sequences and harbored unique genetic features, including novel amino acid polymorphisms in the spike protein. Further characterization will be required to understand their effects. MERS-CoV spillover into humans poses considerable public health concerns. Our findings indicate surveillance and phenotypic studies are needed to identify and monitor MERS-CoV pandemic potential.

____

#abstract #betacoronavirus #camels #coronavirus #covid #COVID19 #health #merbecovirus #mersCov #research #sarsCov2 #SAUDIARABIA #vaccine


Enhanced immune #evasion of #SARS-CoV-2 variants #KP311 and #XEC through N-terminal domain #mutations


Source: Lancet Infectious Diseases, Correspondence, https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00738-2/fulltext?rss=yes

{Excerpt}

KP.3, a subvariant of JN.1, has rapidly emerged as the dominant strain of SARS-CoV-2 in several countries, and has been designated as a Variant Under Monitoring. Previous studies indicate that the unique Q493E substitution in KP.3 Spike glycoprotein enhances its receptor ACE2-binding affinity and immune evasion, enabling it to outcompete KP.2.1–6 Notably, KP.3.1.1, which only carries one additional S31 deletion compared to KP.3, has surpassed KP.3 to become the new dominant strain globally (figure A; appendix p 4).7 Meanwhile, XEC, a recombinant variant of KS.1.1 and KP.3.3, shows strong potential to become the next dominant strain, rapidly expanding across Europe and North America. Compared with KP.3, XEC has only two additional spike mutations, F59S and T22N (appendix p 4). Both S31del and T22N introduce potential glycosylation on the N-terminal domain. Consequently, there is an imperative need to characterise the antigenicity and infectivity of KP.3.1.1 and XEC.

(…)

____

#abstract #coronavirus #covid #COVID19 #health #pandemic #research #sarsCov2